The DEA has found an average of 2.4 milligrams of fentanyl in the pills they test (DEA, 2024). The large number of overdose deaths involving fentanyl highlights the need to ensure people most at risk can access care, as well as the need to expand prevention and response activities. Deaths from fentanyl — the synthetic, often deadly opioid frequently present in illicit street drugs — have contributed to the United States’ soaring opioid overdose deaths in the last decade.
Over 115 Million Pills Containing Illicit Fentanyl Seized By Law Enforcement In 2023
However, skin absorption can be affected in unknown ways, so avoid touching your eyes, nose, or mouth and wash your hands with soap and water as soon as possible (Washington State Department of Health, n.d.). Fentanyl is 100 times stronger than morphine and 50 times stronger than heroin (DEA, n.d.). It is so potent that just 2 milligrams can cause someone to experience a fatal overdose (DEA, 2024). An individual’s tolerance to fentanyl will impact the amount required to cause a fatal overdose.
Endorphins, the substances in the body that normally bind to opioid receptors and naturally relieve pain, are also connected with “pleasure centers” in the brain. Repeated activation of these centers by narcotic drugs is suspected of playing a role in drug addiction. Hence, fentanyl, similar to other narcotic drugs, carries a high risk of addiction and accidental overdose. In the second decade of the 21st century in the United States, fentanyl was one of the deadliest drugs of abuse. Naloxone/naltrexone are robust opioid antagonists that function by blocking µ-receptors. The FDA has approved these antidote medications for emergency treatment of patients with known or suspected opioid overdose experiencing respiratory and/or central nervous system (CNS) depression.
Overdose Deaths Involving Psychostimulants With Abuse Potential, 1999-2023

These were linked to over 5,100 opioid suppliers’ IDs and nearly 2,800 buyers’ IDs. Using a programming language to probe the dark web, the researchers found more than 248,000 opioid-related listings on 10 anonymous online marketplaces. Champagne-Langabeer is an assistant professor of health informatics at the University of Texas Health Science Center at Houston. The University of Kentucky Public Relations and Strategic Communications Office provides a weekly health column available for use and reprint by news media.
National Coalition Against Prescription Drug Abuse
Always have materials (Narcan and the testing strips) and emergency numbers handy. If you suspect someone is having a fentanyl or other opioid overdose, you can administer Narcan to try and revive them. Even if you aren’t 100% sure, Narcan will not hurt the person if they aren’t experiencing an opioid overdose. After administering Narcan, it is still helpful to call for medical help. Two important harm reduction tools are the medication naloxone (also known by its brand name Narcan) and fentanyl test strips.
People can test positive for fentanyl for 3 to 5 days after last use. Once you’ve been taking fentanyl for a while, your body gets used to it and stopping can be very hard. It can be hard to function without the drug in your system.
Prevention Tips
Fentanyl is used as needed to treat breakthrough pain but not more often than four times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. When it is intentionally misused, fentanyl often shows up as a powder, spiked on blotter paper or is mixed with or substituted for heroin and other street drugs. Fentanyl is an extremely dangerous substance, and has been responsible for many fatal overdoses in the past several years.
- To buy his fentanyl, the man uses “darknet” sites, which are unlisted on search engines, rely on a special private browser for access, and don’t tie his username to his identity.
- Drug dealers have used fentanyl analogs as an adulterant in illicit drug supplies since 1979, with fentanyl-related overdoses clustered in individual cities.
- After a fentanyl treatment, you may have side effects that hinder your thinking and reactions or cause dizziness or drowsiness.
- Illicitly manufactured fentanyl is internationally synthesized in China, Mexico and India, then exported to the United States as powder or pressed pills.
Do People Buy Fentanyl: Understanding The Controversial Drug

Fentanyl, a potent synthetic opioid, has been making headlines due to its alarming involvement in overdose deaths. In this article, we delve into this controversial drug and shed light on the reasons behind its purchase. Using fentanyl regularly can lead to an opioid use disorder (OUD).
Breathing air in a room with fentanyl can’t make you sick. Medical experts said fentanyl isn’t volatile, meaning it doesn’t easily become a vapor, which means you’re not going to become sick from breathing near it. Experts said fentanyl doesn’t just float up into the air and unintentionally expose people nearby. In 2022, the advocacy group Facing Fentanyl designated Aug. 21 “National Fentanyl Prevention and Awareness Day,” to honor the people who have died from fentanyl and to increase public awareness of its toll. Fentanyl use can result in death even with one dose, especially if a person accidentally takes it incorrectly.
We’ll update this article as more up-to-date information becomes available. Watch a video on How to use fentanyl test strips from Prevent Overdose-Rhode Island. Learn more about law enforcement and overdose response here. There is no way to know how much fentanyl is in something based on look, smell, or taste. Any opioid pill not from a pharmacy is highly likely to be fake and contain fentanyl. The biggest risk factor is that people are often exposed unintentionally and don’t know to take the proper precautions to use this drug safely.
- Naloxone can reverse symptoms of fentanyl and other opioid poisoning.
- Fentanyl is synthetic, which means it is made entirely in laboratories and has no natural ingredients.
- The transdermal patches can last for up to 12 to 24 hours after the patch has been removed.
- Because fentanyl is so strong, it takes only a small dose of the drug to cause death.
- Because the drug is less expensive than other opioids, people making it illegally commonly mix it into drugs such as heroin, cocaine, or methamphetamines.
US Overdose Deaths, Select Drugs Or Drug Categories, 1999-2023
In 2022, the US Drug Enforcement Agency seized brightly colored fentanyl pills and powder (“rainbow fentanyl”), demonstrating that fentanyl can come in various colors and formulations. It’s one of the most common drugs involved in overdose deaths. You can become dependent on fentanyl even if you’re taking it as directed by a doctor. This means you’ll experience withdrawal symptoms once you stop taking it. People who use drugs might not be aware they are taking fentanyl, yet the reality is that fentanyl-laced drugs are prevalent.

Alternatively, some people may take illegally manufactured fentanyl for its heroin-like effect. Sometimes, individuals mix it with other drugs because of its potency. A person exhibiting the symptoms of overdose should get immediate medical attention. With an overdose of fentanyl, the brain experiences hypoxia.
US Overdose Deaths Involving Prescription Opioids, 1999-2023

Because a smaller dose has a similar effect relative to other opioids, it is also easier to smuggle. The researchers hope their findings will prompt policymakers to take steps to curb dark web sales of opioids. Postings included product photos and reviews, as well as instructions for buying the items. Soon after a product had been posted and sold, the seller and site disappeared, according to the report recently published in the Journal of Medical Internet Research. That included just over 28,100 opioid product listings and over 13,500 opioid promotional and review forum traces.

Call your pharmacist or the manufacturer if you have questions or need help disposing of unneeded medication. Keep this medication in the packaging it came in, tightly closed, and out of reach of children, and in a location that is not easily accessible by others, including visitors to the home. Store fentanyl in a safe place so that no one else can use it accidentally or on purpose.
Q: What Are The Signs Of Fentanyl Addiction?
Despite these programs, the internet has made buying almost anything online an option. It’s crucial to use extreme caution when getting medication or products marketed as “natural alternatives” from someone other than your health care provider. There have been situations where people thought they were buying natural products, including weight-loss supplements, cannabis and anti-anxiety medications, and instead got fentanyl-laced drugs. Fentanyl misuse can lead to unconsciousness, compromise respiratory function and lead to overdose resulting in death. Fentanyl may cause serious harm or death if used accidentally by a child or by an adult who has not been prescribed the medication. Even partially used fentanyl may contain enough medication to cause serious harm or death to children or other adults.