Just two milligrams of fentanyl can be fatal for the average person. When fentanyl is mixed into other drugs, it cannot be seen, smelled, or tasted, and it’s nearly impossible to distinguish counterfeit pills containing fentanyl from legitimate ones. Fentanyl is a synthetic opioid that is well-known for its extreme potency. Either way, that might seem like a high cost for a small amount of drugs. However, fentanyl is chosen by illegal drug producers and drug dealers for its strength and affordability. Its inclusion makes street drugs more potent and cheaper to make, driving its frequent use in the production of illicit substances.
If A Person Has Naloxone, Is Fentanyl Safe To Use?
Information provided by NIDA is not a substitute for professional medical care or legal consultation. In high enough doses, opioids can cause breathing to stop completely. Fentanyl’s strength increases this risk of overdose substantially. Synthetic opioids sold illicitly can be mixed with heroin or cocaine, which amplifies its potency and potential danger. This is particularly dangerous if an individual who uses illegal substances like heroin or intentionally misuses prescription drugs is unaware that fentanyl could be in it. Prescription fentanyl is FDA -approved to treat severe pain related to surgery or complex pain conditions.
How Easy Is It To Buy Fentanyl Online? Quite Easy, According To A Senate Report
It’s available both for those who have been prescribed fentanyl and those who are misusing fentanyl. Naloxone may be available without a prescription at community-based programs, local public health groups or local health departments. In many states, the medicine may be requested from a pharmacy without a patient-specific prescription. Despite these programs, the internet has made buying almost anything online an option. It’s crucial to use extreme caution when getting medication or products marketed as “natural alternatives” from someone other than your health care provider. There have been situations where people thought they were buying natural products, including weight-loss supplements, cannabis and anti-anxiety medications, and instead got fentanyl-laced drugs.
Lethal Dose Of Fentanyl
Fentanyl is 100 times stronger than morphine and 50 times stronger than heroin (DEA, n.d.). It is so potent that just 2 milligrams can cause someone to experience a fatal overdose (DEA, 2024). An individual’s tolerance to fentanyl will impact the amount required to cause a fatal overdose. Fentanyl misuse can lead to unconsciousness, compromise respiratory function and lead to overdose resulting in death. You can’t overdose by touching an item containing fentanyl.
Why Is It So Dangerous?
Fentanyl may cause serious breathing problems or death if it is used by people who are not being treated with other narcotic medications or who are not tolerant to narcotic medications. Fentanyl exerts its pain-relieving effects by acting on opioid receptors that occur naturally in the body. Endorphins, the substances in the body that normally bind to opioid receptors and naturally relieve pain, are also connected with “pleasure centers” in the brain. Repeated activation of these centers by narcotic drugs is suspected of playing a role in drug addiction.

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If you suddenly stop using fentanyl, you may experience unpleasant withdrawal symptoms. Fentanyl should be used along with your other pain medication(s). Do not stop taking your other pain medication(s) when you begin your treatment with fentanyl.
Responding To An Overdose

If you or someone you know is struggling with fentanyl use, it is essential to seek professional help. Recovery is possible with the proper support and treatment. If you suspect someone is overdosing on fentanyl, call emergency services immediately.
Tell your doctor if you feel that your pain is not controlled or if your pain increases, becomes worse, or if you have new pain or an increased sensitivity to pain during your treatment with oxycodone. Do not take more of it or take it more often than prescribed by your doctor. Naloxone — also known by the brand names such as Narcan and Kloxxado — is a prescription medication that reverses an opioid overdose. While it works quickly, naloxone is a temporary solution that works for 30 to 90 minutes.
This makes evidence-based harm reduction strategies such as fentanyl test strips, safety planning, and access to safe supply more vital than ever. The fentanyl crisis has become a significant public health issue in recent years. Its potency and widespread availability have contributed to a dramatic increase in opioid-related deaths.
- Your doctor or pharmacist will show you and your family members how to use the medication.
- Talk to your doctor about the risks of using this medication.
- Fentanyl is hepatically metabolized via the CYP450 enzyme system, specifically CYP3A4.
- Once the heart and brain have gone without oxygen for a while, naloxone will not work.
- Although fentanyl patches are a legal form of the drug doctors sometimes prescribe for pain, they are easily abused.
- Fentanyl also can increase feelings of pleasure, often referred to as euphoria.
Illegal drug sales on the streets and in online drug markets are thriving at the expense of our loved ones, supplying potent substances leading to higher rates of overdose than ever before. Being aware if fentanyl is present allows people to implement appropriate harm reduction strategies to reduce the risk of an overdose. Fentanyl moving through the street market comes in a powder form and can be injected, smoked, or snorted.

Fentanyl Is Available In A Variety Of Forms
- However, the amount of time it remains effective depends on the individual.
- In case of overdose, remove the fentanyl from the victim’s mouth and call local emergency services at 911.
- This choice empowers you to integrate recovery seamlessly into your lifestyle, fostering sustainable progress over time.
- This medication should not be prescribed for other uses; ask your doctor or pharmacist for more information.
- NIDA is a biomedical research organization and does not provide personalized medical advice, treatment, counseling, or legal consultation.
It makes him drowsy, but he says people can’t usually tell he just used. For a comprehensive and focused approach, inpatient facilities provide an immersive healing environment. These facilities offer a structured and closely monitored setting where individuals can commit fully to their recovery. Guided by medical professionals and an array of therapeutic modalities, inpatient programs equip you with the necessary tools to break free from the grip of addiction.

Hence, fentanyl, similar to other narcotic drugs, carries a high risk of addiction and accidental overdose. In the second decade of the 21st century in the United States, fentanyl was one of the deadliest drugs of abuse. Typically, a fentanyl overdose manifests as an extrapolation of its pharmacological side effects. Although the clinical scenarios may vary among patients, one of the main concerns is the level of expression of OIRD.